Improved flow cytometric assessment reveals distinct microvesicle (cell-derived microparticle) signatures in joint diseases.

INTRODUCTION: Microvesicles (MVs), earlier referred to as microparticles, represent a major type of extracellular vesicles currently considered as novel biomarkers in various clinical settings such as autoimmune disorders.However, the analysis of MVs in body fluids has not been fully standardized yet, and there are numerous pitfalls that hinder the

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The evolution of the Global Burden of Disease framework for disease, injury and risk factor quantification: developing the evidence base for national, regional and global public health action

Abstract Reliable, comparable information about the main causes of disease and injury in populations, and how these are changing, is a critical input for debates about priorities in the health sector.Traditional sources of information about the descriptive epidemiology of diseases, injuries and risk factors are generally incomplete, fragmented and

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Economic Policy and Analysis of the Draft Forcast by the Ministry of Economic Development of the Russian Federation Up to 2024

Topicality of the document prepared by the Ministry Mug Racks of Economic Development of the Russian Federation -the Forecast of the Social and Economic Development of the Russian Federation up to 2024 (hereafter referred to as the MED Forecast) implies both estimation of principle factors, which can affect the development of economy in the country

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Distinct changes in CREB phosphorylation in frontal cortex and striatum during contingent and non-contingent performance of a visual attention task

The cyclic-AMP response element binding protein (CREB) family of transcription factors has been implicated in numerous forms of behavioural plasticity.We investigated CREB phosphorylation along some nodes of ANTIOXIDANT NETWORK corticostriatal circuitry such as frontal cortex (FC) and dorsal (caudate putamen, CPu) and ventral (nucleus accumbens, NA

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